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・ Thromboelastometry
・ Thrombogenicity
・ Thrombohemorrhagic event
・ Thrombolite
・ Thrombolysis
・ Thrombolytic drug
・ Thrombolytic Science International
・ Thrombomodulin
・ Thrombophilia
・ Thrombophlebitis
・ Thromboplastin
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・ Thrombopoietic agent
・ Thrombopoietin
・ Thrombopoietin mimetics
Thrombopoietin receptor
・ Thromboregulation
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・ Thrombospondin
・ Thrombospondin 1
・ Thrombotic microangiopathy
・ Thrombotic storm
・ Thrombotic thrombocytopenic purpura
・ Thromboxane
・ Thromboxane A2
・ Thromboxane B2
・ Thromboxane receptor
・ Thromboxane-A synthase
・ Thrombus


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Thrombopoietin receptor : ウィキペディア英語版
Thrombopoietin receptor

The thrombopoietin receptor also known as the myeloproliferative leukemia protein or CD110 (Cluster of Differentiation 110) is a protein that in humans is encoded by the MPL (myeloproliferative leukemia virus) oncogene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4352 )
== Discovery ==

In 1990 an oncogene, v-mpl, was identified from the murine myeloproliferative leukemia virus that was capable of immortalizing bone marrow hematopoietic cells from different lineages. In 1992 the human homologue, named, c-mpl, was cloned. Sequence data revealed that c-mpl encoded a protein that was homologous with members of the hematopoietic receptor superfamily. Presence of anti-sense oligodeoxynucleotides of c-mpl inhibited megakaryocyte colony formation.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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